When I use alt+tab to return to my desktop, then later try to re-activate the game, it doesn't go back to full-screen properly. The game appears, but my taskbar remains in place, with the game shifted to the right (My taskbar is on the left side of my screen).
I have a workaround for the issue: I just have to switch the game to windowed mode, then switch it back to full-screen with the in-game options.