I was in the middle of a FSC run placing down a statue (if it matters), with my screen was suddenly filled with vertical alternating black and yellow stripes. My computer was working fine (HDD activity was normal), but I couldn't Alt+F4, Alt + Tab, Ctrl + Alt + Del, or anything. Restarted my computer and tried running SK again, and same thing happened when I got to title screen - blue and black stripes. I restarted again and left Task Manager open while SK was starting, and I caught a Windows Alert: "The graphics driver crashed, and recovered".
So, using Radeon HD 7770, the drivers SHOULD be updated, and I'm playing through Steam.