I've noticed that Catalyzer shots make tiny explosions upon striking an object, allowing them to hit multiple targets at once (particularly blocks) if they're close enough together, which is cool and makes sense for the flavor and visual cues of the gun.
I've also notices, however, that charged Catalyzer shots can rarely be applied to multiple enemies at once, if they're both moving and very close together. I noticed this for the first time down in the clockworks, and have since been able to replicate it fairly easily on the shufflebots in the Advanced Training Hall. I've used both a Virulent and Toxic Catalyzer, so it's not limited to one particular type of gun.
Is this a bug or just an unintended feature? I can't imagine being able to do it reliably out in the field in most situations, but it seems to come up pretty frequently in arenas or Gremlin stages where there are a lot of things chasing me.
Everything, including every gun in the game can hit multiple targets if you shot between them. For example a Magnus wich shots only one bullet at a time, you can even hit 2, 3 or sometimes 4 devilites at the same time, if they stay close to each other.
mfg :)