...OOO blocked out:
- armor offensive bonuses
- weapon UVs
- totally disabled sword and gun charge attacks
- lowered attack speed for swords and guns and raised charge time for bombs by two stages for each
- battle sprite perks
- weapon and trinket slots and removing the arsenal stations
- totally removed vitapod, heart and consumables drops
- put enemy gates for each spawn not allowing to progress without killing the enemies
- penalty of death would be having to retire the run
I would play that like hell, even as a new difficulty.
That's a whole new difficulty level.