The subject line seems... confusing, I guess? Let me explain.
If I get hit on the head by say, a lumber, will my equipped helm be the only thing factored in to the damage I take? Like.. if you get hit on the head, does it make a difference what armor you have? Likewise, if you get hit below the "neck" (I don't think we have those...), will the helm you have make any difference? Is the damage calculated as 2 separate values (one for head, one for body) that get added to calculate how much health you lose, or as one value based on your total defenses?
The defense from your armor and the defense from your helm combine into one personal defense.
Hit location isn't separated. You're hit or you're not.