Seems that in this mission, Bosco doesn't quite look the way he does in the overworld. What I mean to say is that in the mission, when you speak to him, he has the hood and his color is cobalt, where in the overworld, he would have the shrunken eyes, the stranger hat, and his color was yellow.
Also, I noticed that when progressing through dialogue (i.e. when you click on the text below to continue), the animations of the characters on screen reset, so they kind of twitch a little, or a lot if they happen to be doing something.
So yeah.
There was also an additional issue with the HUD on the bottom.
It doesn't seem to respond to the cursor, so dropping vitapods isn't possible anymore.