Very interesting effects:
-Colour distortions (haven has sunset-like red-pink colour, distorted colours in wolver den and so on)
-Cant see drop of coins, heat, stuff on respawning things (hearts, vials on FSC levels and so on)
-Cant see any kind of attack (*breathe* attacks of slugs, charge of combuster and so on)
-Cant see shock/fire status effects on knight

Tested on low and medium graphics
Shoots in my Steam profile:
http://steamcommunity.com/id/stalexindalab/screenshot/578996451135115203 - no coins and heat after opening Vana's boxes
http://steamcommunity.com/sharedfiles/filedetails/?id=167025952 - distorted colours in clockworks
http://steamcommunity.com/sharedfiles/filedetails/?id=167179017 - crimson haven
http://steamcommunity.com/sharedfiles/filedetails/?id=167179164 - attacking wolf looks strange

Hope this problem have solution different from buying new PC :)