Just a few things, I'll leave this as short and succinct as possible.
Calling for 'Help':
It's really hard to notice when a teammate is calling for help (num0, /help, etc.). Perhaps have a HUD waypoint that makes it obvious that your teammate needs help and in which direction they are. If someone is spamming it just to be annoying, they can be 'ignored', or it can be disabled entirely in the options. When I or one of my mates are frozen and surrounded by mecha knights or cornered by a trojan, it'd be nice if the rest of the party could be alerted asap.
Vials:
I'd like to be able to drag and drop my vials. It's rare that I need to, but say I'm fighting Lord Vanaduke and my useables inventory is full, and I want to pick up a poison or freeze vial, I don't want to take the time to hoist and throw a vial that I don't want when I'm wearing full Chaos and a Swiftstrike. Or maybe I just want to set a couple down for a sec and pick them up later, who knows, but I'd like to have that feature back.
Blue Pills:
How come I'm able to overdose? I'm not able to use red pills if my HP is full, but if I have no status ailments I'm able to burn all my blues. When I'm on fire and letting out a blitz charge, I want to use a blue right away after the attack animation, so I'll spam '2' until one gets used, but I'll often use two when I only want to use one. This one is really my error, as I should simply not spam and the problem will be solved, but maybe consider it?
Vials rarely drop during the fight against Vanaduke. You're lucky if you get a vitapod from the zombies.
And the fact that you're wearing chaos and swiftstirke changes nothing. You can safely throw the vials when the enemy is dead/frozen/busy with an ally.
You chose the worst argument to defend a good idea.